Editorial tool

Evidence grade calculator

Internal editorial tool for applying the Peptide Authority A–E methodology consistently to a peptide / claim combination. Pick the evidence characteristics; the tool returns a suggested grade plus safety and regulatory flags. The output is editorial guidance, not a substitute for editor judgement.

Study type and species

Sample size (or analogue for animal / preclinical)

Endpoint relevance

UK regulatory status

Adverse-event evidence

Conflict / context note (editor reference, optional)

Editor notes

The score is guidance, not a verdict. Editor judgement overrides on edge cases.
Two reviewers should agree before publishing a grade.
When in doubt, prefer the lower grade and explain the uncertainty on the page.
Re-grade when significant new trial data publishes — see the editorial standards.